Which of the following antibiotic is not involved in the inhibition of specific enzyme systems?
Answer: C
The sulphonamides have their antibacterial attack directed towards a specific essential enzyme. Their structure is related to p-aminobenzoic acid (PABA) which is a precursor to their synthesis of the essential coenzyme tetrahydrofolic acid (THFA).
The antibiotic penicillin was discovered by which of the following researchers?
Answer: C
Alexander Flemming identified the famous antibiotic penicillin obtained from the mold Penicillium sp.
Which of the following chemothearpeutic agent is extensively used because of their antibacterial effectiveness in a wide range of bacterial infections?
Answer: D
Sulfadiazine and sulfamerazine are extensively used because of their antibacterial effectiveness in a wide range of bacterial infections and because they are least likely to produce toxic reactions in the patient.
Sulfonamides and arsphenamine are similar in their specificity for a special group of organism.
Answer: B
Sulfonamides are not specific for a special group of organisms, as arsphenamine is for Treponema, but are effective against a large variety of pathogenic organisms.
Sulfanilamide was synthesized by which of the following research scientists?
Answer: B
Domagk showed the therapeutic value of a group of compounds known as the sulfonamides and Sulfanilamide was the first compound in this group to be synthesized by Gelmo in 1910.