Which of the following antibiotic is not involved in the inhibition of specific enzyme systems?
The sulphonamides have their antibacterial attack directed towards a specific essential enzyme. Their structure is related to p-aminobenzoic acid (PABA) which is a precursor to their synthesis of the essential coenzyme tetrahydrofolic acid (THFA).
The antibiotic penicillin was discovered by which of the following researchers?
Alexander Flemming identified the famous antibiotic penicillin obtained from the mold Penicillium sp.
Which of the following chemothearpeutic agent is extensively used because of their antibacterial effectiveness in a wide range of bacterial infections?
Sulfadiazine and sulfamerazine are extensively used because of their antibacterial effectiveness in a wide range of bacterial infections and because they are least likely to produce toxic reactions in the patient.
Sulfonamides and arsphenamine are similar in their specificity for a special group of organism.
Sulfonamides are not specific for a special group of organisms, as arsphenamine is for Treponema, but are effective against a large variety of pathogenic organisms.
Sulfanilamide was synthesized by which of the following research scientists?
Domagk showed the therapeutic value of a group of compounds known as the sulfonamides and Sulfanilamide was the first compound in this group to be synthesized by Gelmo in 1910.